EatQOD

I take standard doses of B-vitamins (100% RDA) plus a much larger dose of B12 (0.5 - 1.0 mg/day), since I'm older and older people often have trouble absorbing B12.

There's a lot of controversy about the role of homocysteine and whether lowering it using vitamin cocktails of folic acid, pyridoxine, and B12, help patients with high cardiovascular risk.

There were two large studies pubished today in NEJM that suggested that there was no benefit of taking such vitamin cocktails, and in one study, a vitamin cocktail that included a very large dose of B6 (pyridoxine) actually appeared to increase cardiovascular risk. Plus in another study, (HOPE) the vitamin cocktail lowered the risk for stroke, but the risk for unstable angina was increased. For a discussion of these issues, see:

http://www.medpagetoday.com/2005Meeting ... ng/tb/2836

I still think that it's prudent to take normal dose B vitamins during QOD eating (100% RDA); for B12 - it depends on your age and how worried you are about B12. I continue to take the higher dose B12, based on some evidence that's presented in the QOD Diet book, but the benefits of doing this are not very clear cut in terms of "hard outcomes". I take normal RDA for pyridoxine and folic acid (just a regular B-multivitamin with C).

JT